CV

Bruno Cuevas Zuviría, PhD

Experience

  • Assistant professor — Universidad Politécnica de Madrid 2026-05 — Present
    • 2026-05/2026-08 - Visiting the Kaçar lab at University of Wisconsin-Madison!
  • Post-doctoral researcher — Universidad Politécnica de Madrid 2025-03 — 2026-04
    • Study of the effects of multiple infections on plant virus infection risk
  • Margarita Salas Post-doctoral fellow — Universidad Politécnica de Madrid 2024-01 — 2024-12
    • Margarita Salas fellow working on synthetic biology, biocomputation, and its interface with the origin of life.
  • Margarita Salas Post-doctoral fellow — University of Wisconsin-Madison 2022-02 — 2023-12
    • Margarita Salas fellow working on the evolution of proteins and the origins of life.
  • Post-doctoral researcher — University of Wisconsin-Madison 2021-09 — 2022-02
    • Post-doctoral researcher working on the evolution of proteins and the origins of life.
  • Pre-doctoral researcher — Universidad Politécnica de Madrid 2018-01 — 2021-07
    • Predoctoral researcher working on the development of electron density prediction models based on machine-learning.

Education

  • BSc in Biotechnology, Computational biology Universidad Politécnica de Madrid - 2012-09 / 2016-07.
  • MSc in Mathematical Modeling for Science and Engineering, Complex Systems Universitat Autonoma de Madrid - 2016-09 / 2017-07.
  • PhD in Biotechnology of Plants and their Associated Microorganisms Universitat Autonoma de Madrid - 2018-01 / 2021-07.

Skills

  • Python
  • Neo4J
  • Flask
  • Molecular dynamics
  • Structure prediction
  • Machine learning
  • Web development
  • Data analysis
  • Adobe Illustrator
  • Blender

Publications

Year Title Journal DOI
2025 ChemOrigins: a community-curated database for origins-of-life chemistry Royal Society Interface Focus 10.1098/rsfs.2025.0034
2025 Structural evolution of nitrogenase over 3 billion years eLife 10.7554/eLife.105613.4
2025 Evolutionary Dynamics of RuBisCO: Emergence of the Small Subunit and its Impact Through Time Molecular Biology and Evolution 10.1093/molbev/msae268
2025 Why cellular computations challenge our design principles Seminars in Cell and Developmental Biology 10.1016/j.semcdb.2025.103616
2024 An Agent-Based Model Shows How Mixed Infections Drive Multiyear Pathotype Dynamics in a Plant–Virus System Phytopathology 10.1094/PHYTO-06-23-0214-R
2024 Emergence of an Orphan Nitrogenase Protein Following Atmospheric Oxygenation Molecular Biology and Evolution 10.1093/molbev/msae067
2023 The modular biochemical reaction network structure of cellular translation npj Systems Biology and Applications 10.1038/s41540-023-00315-3
2023 Informatic Capabilities of Translation and Its Implications for the Origins of Life Journal of Molecular Evolution 10.1007/s00239-023-10125-0
2022 Learning electron densities Quantum Chemistry in the Age of Machine Learning 10.1016/B978-0-323-90049-2.00022-6
2021 Machine Learning of Analytical Electron Density in Large Molecules through Message-Passing Journal of Chemical Information and Modeling 10.1021/acs.jcim.1c00227
2021 Environment and coordination of FeMo-co in the nitrogenase metallochaperone NafY RSC Chemical Biology 10.1039/d1cb00086a
2021 The key to the allergenicity of lipid transfer protein (LTP) ligands: A structural characterization Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 10.1016/j.bbalip.2021.158928
2020 Analytical Model of Electron Density and Its Machine Learning Inference Journal of Chemical Information and Modeling 10.1021/acs.jcim.0c00197
2020 A computational structural study on the DNA-protecting role of the tardigrade-unique Dsup protein Scientific Reports 10.1038/s41598-020-70431-1
2020 Dynamic plasticity of the lipid antigen-binding site of CD1d is crucially favoured by acidic pH and helper proteins Scientific Reports 10.1038/s41598-020-62833-y
2020 Structural dynamics of the lipid antigen-binding site of cd1d protein Biomolecules 10.3390/biom10040532
2019 Energy landscapes of ligand motion inside the Tunnel-like cavity of lipid transfer proteins: The case of the Pru p 3 allergen International Journal of Molecular Sciences 10.3390/ijms20061432
2018 A comparative study of human saposins Molecules 10.3390/molecules23020422